The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine.

Postdoctoral Scientist ‘Vascular Disease and Brain Health’ (f/m/x)

Code: 1132/2022/9

We are looking for an experienced researcher with leadership ambitions, to contribute to ongoing research projects and initiate new research projects focusing on the relation between the vascular system and brain health.

The job holder will be part of the Population Health Sciences group, led by Prof Dr Dr Monique M B Breteler, and located at the headquarters of the German Center for Neurodegenerative Diseases (DZNE) in Bonn. Our research is primarily based on the Rhineland Study, a prospective cohort study that emphasizes deep phenotyping. The cohort currently includes more than 10,000 participants with further recruitment ongoing and follow-up examinations starting in October 2022. The comprehensive data collection encompasses detailed structural and functional brain imaging, cognitive and behavioral assessments, cardiovascular investigations, sensory systems assessments, questions on medical history, lifestyle, nutrition and mental health, assessment of medication intake, and collection of biomaterials. Moreover, we have already obtained extensive blood-based biomarker data from our participants, including (epi-)genomic arrays, RNA-seq data, metabolomics, lipidomics, and immune profiling, as well as gut microbiome analyses.

Your tasks

Leveraging the extensive Rhineland Study data, you will investigate causes of cardio- and cerebrovascular aging, and their relation with neurodegenerative diseases. This includes conceptualizing research questions, formal data analyses, interpreting and reporting results, and drafting and revising manuscripts. In addition to contributing to ongoing projects, you will develop your own research projects as they fit within the general research interests of our group. Furthermore, you will contribute to the management of data acquisition, cleaning and post-processing, be involved in the supervision of PhD and master students, and actively participate in national and international collaborative studies.



  • You hold a PhD in epidemiology, medicine, (bio)medical sciences or other relevant discipline
  • Basic medical knowledge is a pre-requisite 
  • Several years of experience in epidemiological research or large-scale observational studies
  • Strong data analytical skills are required, experience with omics analyses is desirable
  • A track record of publishing high quality scientific papers
  • Excellent work ethic, initiative, and time management skills
  • Flexibility and strong social skills
  • Strong communication and writing skills in the English language are a prerequisite

We offer

  • An interesting and challenging position on the forefront of health research
  • Work in a highly interdisciplinary and international team to address pressing health issues related to aging
  • Excellent scientific infrastructure with state-of-the-art research and computational facilities
  • Excellent publication opportunities and great potential for the further development of your own research profile
  • Active encouragement and support of personal development
  • The position is initially limited to 2 years
  • Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD Bund).

How to apply

Interested applicants should submit, as one single PDF file, a CV, transcripts, 3 references, and a cover letter describing your motivation to apply for this position, including research interests and experience, through the link below.

Review of applications will begin immediately and continue until the position is filled.

For inquiries about the position, please contact Prof Dr Dr Monique Breteler at

Apply here



Contact details

Prof. Dr. Dr. Monique Breteler

Working hours


Contract length

2 years, extension possible

Payment, social benefits

according to TVöD Bund

Application deadline

January 15th, 2024

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply. Please note that as an employee of the DZNE Bonn, you are subject to facility-related compulsory vaccination against the COVID-19 virus (according to § 20a of the Infection Protection Act).