The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

Research Technician (f/m/d) - BTA/CTA/MTA

Code: 1070/2022/4

We are looking for a highly motivated Research Technician to join our research group “Population & Clinical Neuroepidemiology” at the headquarters of the German Center for Neurodegenerative Diseases (DZNE) in Bonn. Using deep (endo)phenotypic data obtained in the context of both population-based and clinical cohort studies, we aim to identify the risk factors, causes as well as trait and state markers of neurodegenerative diseases through application of epidemiological and bio-informatics approaches.

As part of a project funded by the European Research Council, in which we aim to assess the role of genomic instability and somatic mutations in the pathogenesis of neurodegenerative diseases, we hope to find a technician who will support high-throughput bio-sample selection and preparation, extracellular vesicle isolation and characterization, as well as our next-generation sequencing and functional validation experiments.


Your tasks

  • Bio-sample selection and preparation
  • Extraction of nucleic acids from blood
  • Isolation and characterization of extracellular vesicles from blood
  • Extraction of nucleic acids and proteins from extracellular vesicles
  • DNA and RNA library preparation for high-throughput (long-read) sequencing
  • Testing of different protocols and methods for the development of standard operating procedures for high-throughput assays
  • Supporting other lab projects and training of other lab members
  • Taking care of laboratory equipment and ordering of reagents and consumables

Requirements

  • Education as a Lab Technician BTA/CTA/MTA, or a degree in Biology, Biochemistry, or an equivalent degree
  • Experience with library preparation for (targeted) high-throughput next-generation sequencing (Illumina/PacBio)
  • Experience with extracellular vesicle isolation and characterization techniques
  • Good knowledge of molecular biology and biochemistry techniques (Western blotting, quantitative PCR, and immunostaining)
  • Additional experience with immunohistochemistry and (iPSC) cell cultures is desirable
  • Proficiency in German and English
  • Flexible and willing to adapt quickly and enjoy working in a multidisciplinary team

We offer

  • An international environment characterized by a strong focus on science and research
  • Opportunity to learn cutting-edge neuroscience techniques and epidemiological methods
  • Advanced interdisciplinary vocational training
  • Excellent infrastructure, including modern workspaces
  • Employment, payment, and social benefits are consistent with the Public Sector Collective Agreement (TVöD Bund)
  • The initial contract duration will be for 2 years with a possibility of extension

 

How to apply

Interested? Please, send your application in a single pdf file (in English), including:

  • A letter of motivation
  • A detailed and up-to-date CV, including a description of your relevant experience
  • A copy of your academic transcripts
  • At least two references

If we could spark your interest, we look forward to receiving your application at the following link:

For inquiries about the position, please contact Dr. Ahmad Aziz (ahmad.aziz@dzne.de)
Review of applications will begin immediately and continue until the position

Apply here

Site

Bonn

Contact details

Dr. Ahmad Aziz

Working hours

full-time

Contract length

2 years, unlimited contract possible

Payment, social benefits

according TVöD-Bund

Application deadline

31.05.2022

The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply. We would like to point out that as an employee (m/f/x) of the DZNE Bonn you are subject to facility-related compulsory vaccination against the COVID-19 virus (according to § 20a of the Infection Protection Act).