The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

PhD-student (f/m/x) in the group “Translational Protein Biochemistry”

Code: 6025/2022/4

The research group Translational Protein Biochemistry (Prof. Dr. Tobias M. Böckers) focusses on pathomechanisms in neurodegenerative diseases using a wide set of models (i.e. mouse models, expression of relevant proteins in human tissue). In particular, components of the development of Amyotrophic lateral sclerosis (ALS), Frontotemporal Dementia (FTD) and Alzheimer (AD) diseases are of major interest. Furthermore, the research efforts under the keyword "Neurodegeneration as Synaptopathy" and the associated implications for new therapeutic approaches will be intensified. In addition, the role of proteins of postsynaptic density (PSD) in neurodegenerative diseases will be further investigated. Methods in the lab include patient derived induced pluripotent stem cells (hiPSC) differentiated into motor neurons, mouse model analysis, primary neuronal culture and a broad spectrum of molecular and biochemical analyses.


Your tasks

  • Active participation in experimental work, experimental design, data generation, data analyses, and interpretation of results
  • Prepare and write manuscripts for publication in international scientific journals
  • Oral presentation of results on local, national, and international conferences
  • Experimental work includes molecular biology, especially cell culture of induced pluripotent stem cells

Requirements

  • A keen interest in molecular biology and working with induced pluripotent stem cells
  • Experience in molecular biology and handling of pluripotent stem cells is advantageous
  • Successful candidates have a master’s degree in molecular biology, neuroscience, biochemistry (or a master’s degree in a related field)
  • English language is a prerequisite

We are looking for candidates who are open-minded, creative team-player, enthusiastic, have strong analytical skills, think critically, and with good social skills

We offer

  • Working in an international team within a stimulating research environment and with very well equipped laboratories
  • An international environment characterized by a strong focus on science and research
  • A high potential for the individual development of our employees
  • Targeted personnel development
  • Employment, payment and social benefits are consistent with those at other research institutes

Application files

  • CV
  • Motivation letter
  • Bachelor and Master qualifications
  • Recommendation letters
Apply here

Site

Ulm

Contact details

Prof. Dr. Tobias Böckers

Working hours

full-time

Contract length

2 years, extension possible

Payment, social benefits

Employment, payment and social benefits are consistent with those at other research institutes

Application deadline

31.05.2022

You will obtain special skills and knowledge for your scientific qualification at DZNE. The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply.

We would like to point out that as an employee (m/f/x) of the DZNE Ulm, you are subject to facility-related compulsory vaccination against the COVID-19 virus (according to § 20a of the Infection Protection Act).