The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

Postdoctoral Researcher (f/m/x) working on spatial coding in preclinical Alzheimer’s Disease

Code: 4053/2022/5

The DZNE is among the top 10 institutions in Alzheimer’s Disease Research world-wide, and among the top three with respect to citations & collaborations (Elsevier Report 2019).


Your tasks

This position is part of an exciting interdisciplinary project – funded by the Collaborative Research in Computational Neuroscience (CRCNS) initiative – in collaboration with the groups of Ehren Newman and Zoran Tiganj (Indiana University). The overall aim is to characterise how computations in the entorhinal grid cell system are affected in early Alzheimer’s disease (AD). Using a combination of cutting‐edge interactive virtual reality (VR), ultra-high field neuroimaging and pharmacological interventions, you will develop innovative VR paradigms and use computational models to generate novel predictions for altered spatial coding in preclinical AD. Importantly, the successful candidate will closely interact with the collaborating labs, including the possibility for extended research visits.

In addition to hosting research dedicated 3T and 7T MRI and MR-PET scanners, the Magdeburg site of the DZNE provides access to EEG, MEG, TMS and eye tracking systems. Furthermore, the lab has a range of cutting-edge VR setups and entertains multidisciplinary international collaborations. Finally, Magdeburg offers a unique intellectual environment, because spatial navigation is a core theme investigated across several animal and human research groups.

Requirements

For this position, excellent statistical and programming skills (e.g. in Python, R, Matlab) and a strong interest in dementia and spatial navigation are essential. A background in neuroimaging is a plus. You will be thorough, efficient, a good communicator, and enjoy working as part of an international and dynamic team. For further information about this unique opportunity, please email Thomas Wolbers (thomas.wolbers@dzne.de). To learn more about our research, please visit our website and follow us on Twitter (@WolbersLab).

We offer

The position is available from 01 September 2022, initially for 3 years. Interested candidates should submit their applications including a CV, a letter stating research interests and two of the usual references.

Further reading                                             

Segen V, Ying J, Morgan E, Brandon M, Wolbers T (2022). Path integration in normal aging and Alzheimer’s disease. Trends Cogn Sci 26:142–158.

Stangl, M., Kanitscheider, I., Riemer, M., Fiete, I.R. & Wolbers, T. (2020). Sources of path integration error in young and aging humans. Nature Communications.

Stangl, M., Achtzehn, J., Huber, K., Dietrich, C., Tempelmann, C., & Wolbers, T. (2018). Compromised grid-cell-like representations in old age as a key mechanism to explain age-related navigational deficits. Current Biology, 28(7), 1108-1115.

Apply here

Site

Magdeburg

Contact details

Prof. Thomas Wolbers

Working hours

full-time

Contract length

3 years, extension possible

Payment, social benefits

according to TVöD Bund

Application deadline

June 10th, 2022

The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply. You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. We would like to point out that as an employee (f/m/x) of the DZNE Magdeburg, you are subject to the facility-related compulsory vaccination against the COVID-19 virus (according to § 20a of the Infection Protection Act).