The German Center for Neurodegenerative Diseases (DZNE) is a unique non-university research center which is dedicated to the subject dementia and all its areas, as well as other neurodegenerative diseases. The center compasses the full spectrum of fundamental research through population sciences to health care research. The DZNE stands for excellence in research and science management, translation of scientific results into practice, interdisciplinarity and internationalization. It is a research center within the Helmholtz Organization of German research centers. With over 1000 employees from 55 nations, spread over 10 sites, the DZNE is one of the national and international leading research centers in its research field. 

Postdoctoral Researcher (f/m/d)

Code: 2072/2020/2

Your tasks

We are looking for a senior Postdoc to join our Translational Brain Research Group at the German Center for Neurodegenerative Diseases (DZNE) in Munich. We are offering projects involving electrophysiology and in vivo two-photon imaging in order to identify new therapeutical strategies to treat synaptic dysfunction in Alzheimer’s, Parkinson`s disease and neuropsychiatric diseases.

Alzheimer’s disease (AD) and Parkinson`s disease are the most common causes of dementia. We previously found evidence that the alteration of synaptic function is an early event in the disease (Fuhrmann et al. Nature Neurosci. 2010; Peters et al. Acta Neuropath 2018 and EMBO 2019). We aim to understand the loss of synaptic function in animal models of AD and PD by visualizing morphological and functional alterations of synapses in vivo and try to identify new drug targets at synaptic level (Zou et al. EMBO 2016; Blumenstock et al. EMBO Mol Med 2017).



Suitable applicants must have ample experience in slice and /or in vivo electrophysiology or two-photon imaging as well as the ability to perform creative and independent research. Additionally, applicants must have experience in the supervision of PhD students, possess technical knowledge and be experienced in the handling of mice. Applicants must hold a doctoral degree in physiology, neurobiology or related disciplines with a focus on neuroscience.

Interesting research topics with biomedical relevance in a stimulating scientific environment at an internationally competitive level. The projects involve cutting-edge imaging techniques (in vivo two-photon microscopy, in vivo calcium imaging, optogenetics) and electrophysiology, the use of fluorescent reporters, viral vectors and various transgenic animal models. The Translational Brain Research Lab is a leading in vivo imaging laboratory affiliated with the LMU, one of the top three German universities.

The position is available from summer 2020, initially for 2 years, but with a strong intention to be extended for considerably longer time.

Interested candidates should send their applications including a CV with publication list, a brief summary stating research interests and two of the usual references




Contact details

Prof. Dr. Jochen Herms

Working hours


Contract length

2 years, extension possible

Payment, social benefits

according to TVöD Bund

Application deadline


You will obtain special skills and knowledge for your scientific qualification during your activities at the DZNE. The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply.