The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

PhD student (f/m/d) and Postdoc (f/m/d)

Code: 1825/2020/6 - 1826/2020/6

The research group “Dynamics of Neuronal Circuits”, led by Prof. Dr. Gaia Tavosanis, focuses on the development and adult plasticity of the nervous system. We investigate the cellular mechanism underlying the differentiation of neurons and the capacity of remodelling of the adult nervous system at the cellular and circuit level. For this, we combine multiple approaches ranging from classical genetics in Drosophila and molecular biology to high-resolution in vivo microscopy, functional imaging and behavioural paradigms (https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/tavosanis/research-areasfocus/ ).


Your tasks

One PhD student and one postdoc position will be available in the lab starting from September 2020. The two planned projects will focus on:

  1. The cellular mechanisms that support the differentiation of neuronal dendrites (see Stuerner et al., Development 2019). This project will combine the generation of molecular tools for acute manipulation of protein activity with high-resolution in vivo microscopy. We will closely cooperate with neuronal morphology modelling groups.
  2. The circuit mechanisms that support the consolidation of memories in the adult fly brain. Combining detailed anatomical insight and refined genetic tools to manipulate identified neurons, you will investigate how experience and learning modify a circuit’s output. This project is embedded within the frame of the DFG-funded Research Unit FOR 2705 that includes highly interactive groups with complementary expertise (https://www.uni-goettingen.de/en/601524.html ).

Requirements

  • A strong interest in Neuroscience
  • Previous experience in fly genetics, imaging, fly behaviour and functional imaging are preferred, but not a strict requirement
  • Basic experience in programming will be of advantage
  • The lab language is English

We offer

  • A challenging task in a research center that works on the future topics of health research
  • An international environment characterized by a strong focus on science and research
  • A high potential for the individual development of our employees
  • Employment, payment and social benefits are consistent with those at other research institutes
  • Students in the lab are enrolled in the Bonn International Graduate School in Neuroscience (http://bigs-neuroscience.de/)

Highly motivated candidates are welcome to apply with a short letter of intent and their CV including two references. For the PhD student position, please, include current University records.

 

Site

Bonn

Contact details

Prof. Dr. Gaia Tavosanis

Working hours

full-time

Contract length

2 years, extension possible

Payment, social benefits

consistent with those at other research institutes

Application deadline

July 25th, 2020

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply.