The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

Phd student (f/m/d)

Code: 2074/2020/10


Your tasks

The research group “Ex vivo models”, led by Dr. Sabina Tahirovic, is looking for a PhD student with a strong interest in field of neuroinflammation in Alzheimer’s disease (AD). This PhD project will be focusing on identifying signalling pathways promoting microglial clearance of amyloid plaques (see Daria et al., and Sebastian Monasor et al.). The study aims at discovering molecular signals that are responsible for microglial dysfunction and targeted repair by analysing human cells and murine in vitro, ex vivo and in vivo models of AD and applying cell, molecular biology and biochemistry techniques. Our ultimate goal is to facilitate identification of novel therapeutic approaches for neurodegenerative diseases. For more details about our research, please visit our website (https://www.dzne.de/en/research/research-areas/fundamental-research/research-groups/tahirovic/research-areasfocus/).

Requirements

Candidates with a master’s degree in neuroscience (e.g. biology, molecular biomedicine or related subjects) are encouraged to apply. We are looking for highly motivated applicant with good communication and team-working skills, fluent in English and eager to work in an international environment. This project requires excellent cell culture skills and thus prior experience in handling of primary microglia, neurons, induced pluripotent stem cells and organotypic slice cultures is highly desirable. Experience in neuroscience or neuroimmunology research and in vivo models of neurodegenerative diseases (perfusion fixation, tissue sectioning, immunohistochemistry) as well as basic knowledge in confocal microscopy are of advantage.

We offer

  • An interesting and challenging task in a research center that works on the future topics of health research
  • An international environment characterized by a strong focus on science and research
  • A high potential for the individual development of our employees
  • Targeted personnel development
  • Employment, payment and social benefits are consistent with those at other research institutes

Interested candidates should send their applications including motivation letter, CV and references.

 

Site

Munich

Contact details

Dr. Sabina Tahirovic

Working hours

full-time

Contract length

Payment, social benefits

Employment, payment and social benefits are consistent with those at other research institutes

Application deadline

December 31st, 2020

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. The DZNE especially welcomes and encourages disabled individuals to apply.