The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de
2 PhD Positions (f/m/d): “Neuroscientist”
Within the Neuroimmunology and Imaging Group.
Project description: The Neuroimmunology and Imaging group is interested in understanding the role of long‑range projections between brain regions relevant for learning and memory. In one project, we are especially interested in the connectivity of neuronal ensembles between the hippocampus, the entorhinal cortex and the prefrontal cortex. In a second project, we investigate the connectivity between the locus coeruleus and the hippocampus. Within both projects we aim to understand how the connectivity dysfunction relates to learning and memory deficits under AD-like conditions. To investigate these questions, we apply cutting edge in vivo imaging in awake mice and correlate behavior with neuronal activity. We apply chemo- and optogenetics to manipulate specific neuronal subsets relevant for certain learning behaviors (Poll et al. 2020, Nat.Neurosc.). This enables us to causally link neuronal ensemble activity with learning-related behavioral aspects.
Your profile: Successful candidates should hold a Master degree in biology (neuroscience), biophysics, physics (optics), bioengineering, biochemistry or related disciplines. As a prerequisite the candidate should have experience with confocal microscopy (or 2P-imaging), stereotactic AAV-injections, quantitative histology, bioinformatic image data analysis, or behavior experiments with rodents. Programming skills as well as a FELASA B course or equivalent will be beneficial. Creative, highly motivated applicants who are eager to understand how the brain works and enjoy working independently as a member of a highly collaborative team in a stimulating scientific environment are encouraged to apply.
- An interesting and challenging task in a research center that works on the future topics of health research
- An international environment characterized by a strong focus on science and research
- A high potential for the individual development of our employees
- Targeted personnel development
- Employment, payment and social benefits are determined by the Public Sector Collective Agreement (Tarifvertrag für den öffentlichen Dienst – TVöD Bund).
The position is available from 1st of July for four years, interviewing will begin immediately until the position is filled.
Interested candidates should submit their applications including a CV (including copies of Abitur- & Bachelor/Master certificate) and a letter stating research interests via: Application link
Prof. Dr. Martin Fuhrmann
2 years, extension possible
Payment, social benefits
consistent with those at other research institutes
May 15th, 2021
You will obtain special skills and knowledge for your scientific qualification at DZNE. The DZNE is an equal opportunity employer. It especially welcomes and encourages disabled individuals to apply.