DZNE is a world-leading, internationally oriented center for cutting-edge research into diseases of the nervous system. With its outstanding research personalities and state-of-the-art infrastructure, it offers the best conditions for publications and results at the highest level.

Around 1,200 employees at 10 locations in Germany are working together on new approaches to better understand and effectively combat diseases such as Alzheimer's, Parkinson's and ALS.

That is our goal - maybe soon yours too? Become part of the DZNE and support us in realizing our research strategy!

PhD candidate (f/m/x) in Systems Medicine

Code: 1358/2024/10

The research area Systems Medicine (DZNE Bonn site) is recruiting a PhD candidate (65%) in the field of molecular and translational immunomics.

We are a diverse team working on systems medicine approaches in the context of immunology, chronic inflammation, aging, exposome and neurodegenerative diseases. Our research aims to elucidate the molecular mechanisms by which Per- and polyfluoroalkyl substances (PFASs) exposure impacts the immune system, particularly in the context of aging and non-communicable diseases.

We are currently seeking a highly motivated PhD candidate to join our dynamic team working on cutting-edge research at the intersection of state-of-the-art omics technologies, in-vitro models and computational biology. This position offers a unique opportunity to contribute to understand the clinical impact of the ubiquitous chronic exposure to PFAS worldwide. You will collaborate with an interdisciplinary team of experts spanning various fields, including data and information sciences, immunology, environmental sciences and epidemiological studies.

Your role in detail

Your role will involve leveraging high-resolution single-cell multi-omics data and state-of-the-art organoid models to investigate the impact of PFAS on the immune system. You will perform single-cell multi-omics and high-dimensional cytometry experiment, run analyses and established lymphoid organoid systems. This work serves also as a blueprint for the future investigation of the immunotoxicity of various other environmental pollutants.

If you are passionate about addressing impactful questions in systems medicine we encourage you to apply for this PhD candidate position and be part of our transformative research.

For more general information, please also visit the website of Systems Medicine.
https://www.dzne.de/en/research/research-areas/systems-medicine/
 

Your qualifications

• Master or equivalent in immunology, biomedicine, biotechnology, or comparable topics
• Strong research background in immunology, cell biology, and genomics or transcriptomics
• Practical experience in multi-color flow cytometry, molecular and cell biology, and transcriptomics is of advantage
• Practical knowledge of data analysis and machine learning using R or Python is of advantage
• Very good English proficiency
• Enthusiastic and collaborative work attitude
• Ability to work independently as well as in a team

What our employees value

• Innovation and internationality a forward-looking infrastructure, modern laboratory and office equipment, software tools and the opportunity for international exchange with your colleagues from 65 nations
• Work-life balance - we reconcile work and private life with flexible working hours, 30 days' holiday (On top free on Christmas Eve and New Year's Eve) and subsidised job/ Germany ticket options
• Family-conscious corporate culture - because we know that familie is important, we support you with parent-child offices, family services and daycare co-operations
• Health promotion – through our extensive range of company health programmes, in cooperation with Sozialwerk.Bund
• Focus on development - training programmes tailored to your individual needs and annual HR-development meetings for concrete prospects and potential development
• Remuneration and conditions are consistent with those at other research institutes
• Personalised Onboarding - for a good start to your new professional challenge
• A feel-good working environment - our Bonn employees enjoy a campus surrounded by greenery, with on-site parking and public transport connections as well our company restaurant
• The position is initially limited to 3 years

Please submit your application online via the link below as a single pdf file, including your CV (incl. two references) and a brief cover letter (max. 1 page) stating your motivation for and prior experience relating to this offer.

If you have further questions, please contact joachim.schultze@dzne.de. Interviews will take place by video conference, with a possible and subsequent on-site visit to Bonn. The position is available as from January 1st, 2025 and applications will be considered until the position is filled.

Site

Application deadline

30.11.2024