The German Center for Neurodegenerative Diseases (DZNE) is a world-leading internationally oriented research center, committed to discovering new approaches to prevent and treat neurodegenerative diseases. To this end, researchers at ten DZNE sites across Germany pursue a translational and interdisciplinary strategy comprising five interconnected areas: fundamental research, clinical research, health care research, population health science, and systems medicine. www.dzne.de

Postdoctoral Researcher (f/m/d) – in Biomimetic hippocampal prosthesis

Code: 8029/2021/1

The Adult Neurogenesis Lab led by Prof. Dr. Gerd Kempermann and the Biohybrid Neuroelectronics Lab led by Dr. Hayder Amin in Dresden are seeking to recruit a Postdoctoral Researcher to implement a large-scale biomimetic microelectronics platform that simulates the dynamics of hippocampal circuitry in the presence of newly born neurons.

This synergistic position focused on developing a real-time bidirectional Brain-Machine interfacing framework enabling active decoding and communication between a CMOS-chip and a rodent cortico-hippocampal circuit. The successful applicant will develop and implement biomimetic electronics to mimic/integrate the spatiotemporal information transmission within a large-scale hippocampal circuitry empowered by the enhanced computational function of the newly generated neurons. The outcome will profoundly impact science and society – it would offer a better tool for understanding information coding in neural regenerative circuitry and potentially providing novel restorative treatments for neurodegenerative diseases and brain injuries.

The mission of this synergy aims at building a genuinely interdisciplinary research unit where engineers, experimental neuroscientists, and mathematicians team up to foster advances in neuroscience and neurotechnologies


Your tasks

  • Design and implementation of active Brain-Machine Interface as a biomimetic microelectronic prosthetic for a cortico-hippocampal circuit.
  • Implement and develop independently ex-vivo electrophysiological experiments using high-density biosensors (i.e., CMOS-microelectrode array recordings).
  • Apply state of the art methods for processing multidimensional datasets to develop Brain-Machine Interface applications for the use of cortico-hippocampal prosthesis
  • Participate in all aspects of the project, from hardware design, data generation, analyses, interpretation, and publishing results in high-impact journals.
  • Obtain technical, lab management, and grant writing skills
  • Mentor and cross-train junior lab members (e.g., Ph.D. students)
  • Having outstanding capability of literature synthesis, and troubleshooting of technical

Requirements

The ideal candidate should be/have:

  • Enthusiastic, creative team-player, fluent in English with a strong commitment to research
  • Ph.D. in Biomedical Engineering, Physics, Computer science or relevant scientific/technical discipline with a keen interest in hardware implementation and signal processing, and a particular focus on neuroprosthetic devices
  • Prior technical expertise and research proficiency in hardware implementation and circuit modeling
  • Experience in modeling, biostatistics, and complex data analysis methods proven showcase by a GitHub repository or published articles.
  • Experience in programming & scripting skills, preferably in Python
  • Experience in experimental electrophysiology and neural signal processing of neuronal activity datasets obtained by (i.e., microelectrode arrays, extracellular field potential recordings, and patch-clamp)

We offer

  • Advanced interdisciplinary vocational training and high potential for career development.
  • Opportunity to contribute to cutting-edge neurotechniques in a competitive and highly communicative environment.
  • Excellent infrastructure including modern workspaces and very well equiped labs.
  • Dynamic and multicultural environment.
  • Employment, payment, and social benefits are consistent with the Public Sector Collective Agreement (TVöD Bund).
  • The initial contract duration is 2 years with a possibility of extension.

Interested? Please, send your application in a single pdf file (in English), including:

-    a detailed CV

-    1-page letter of motivation

-    1-page statement of scientific achievements and future research interests and plans

-    3 relevant publications

-    Two or three reference letters

The application should be sent via the link below - as soon as possible but before March 15th, 2021. Review of applications will begin immediately and continue until the position is filled. 

For more information about the position but not the application process, please contact Dr. Hayder Amin

 

 

Site

Dresden

Contact details

Dr. Hayder Amin

Working hours

full-time

Contract length

2 years, extension possible

Payment, social benefits

according to TVöD

Application deadline

March 15th, 2021

You will obtain special skills and knowledge for your scientific qualification during your activities at DZNE. The DZNE is an equal opportunity employer. It is committed to employing disabled individuals and especially encourages them to apply.